2154 (Columbia)

January

• Unknown: As Enterprise passes through a "trans-dimensional disturbance," the crew is put into hibernation, leaving Doctor Phlox in control of the ship. (ENT 68: "Doctor's Orders")
• January 8: Captain Archer becomes overly protective of a Xindi Insectoid hatchery, to the point of endangering their mission. (ENT 69: "Hatchery")

February

• February 3: Finding the superweapon on Azati Prime, Captain Archer embarks on a suicide mission to destroy it, and Enterprise suffers a devastating attack by the Xindi. (ENT 70: "Azati Prime")
• February 3: Enterprise, now heavily damaged, seeks a warp coil from an alien vessel but is forced to steal it. (ENT 71: "Damage")
• February 8: Captain Archer deals with the loss of 18 crew members and continues negotiations with two of the five Xindi species. (ENT 72: "The Forgotten")
• February 10: The Enterprise crew meets their own descendants from an alternate timeline. (ENT 73: "E²")
• February 11: Captain Archer speaks with the Xindi Council, sparking a civil war for control of the superweapon. (ENT 74: "The Council")
• February 13: Captain Archer seeks the support of the Xindi Aquatics in order to tip the war in their favor. (ENT 75: "Countdown")
• February 14: The final showdown with the Reptilians and their Guardian allies occurs. (ENT 76: "Zero Hour")
• February 14: "The Expanse" (Star Trek: Encounters) (ENT)
• February 14: After destroying the Xindi weapon, Enterprise finds itself in the 20th century during World War II with Nazis in control of the northeastern USA. (ENT 77: "Storm Front, Part I")
• February 14: Archer joins Silik to stop the alien Nazis, restore the timeline and end the Temporal Cold War. (ENT 78: "Storm Front, Part II")
• Unknown: Enterprise is welcomed home after saving Earth and the crew takes a much needed vacation. Tucker & T'Pol visit Vulcan, where T'Pol must consider marriage to Koss. Erika Hernandez becomes captain of Columbia and renews her acquaintance with Archer. Phlox encounters prejudice on Earth. (ENT 79: "Home")

May-October

• May 17: Dr. Arik Soong restores his relationship with his genetically-enhanced "children:" the Augments. (ENT 80: "Borderland")
• Unknown: A space station crew is held hostage as Dr. Arik Soong and his Augments work to obtain hundreds of Augment embryos in hopes of creating an Augment population. (ENT 81: "Cold Station 12")
• May 27: Dr. Arik Soong finds himself overthrown as "father" of the Augments and Archer rushes to prevent the destruction of Qu'vat, a Klingon colony. As a result of his dashed hopes of enhancing Humans, Soong turns in a new direction of research. (ENT 82: "The Augments")
• Unknown: "Mother Nature's Little Reminders" (Strange New Worlds 09) (ENT)
• Unknown: Earth's embassy on Vulcan is partially destroyed by a bomb, killing Admiral Forrest. Archer & T'Pol travel to Vulcan in search of an alleged terrorist group blamed for the explosion, of which T'Pol's mother is a member. (ENT 83: "The Forge")
• Unknown: Archer & T'Pol find T'Pau and T'Pol's mother, and learn that Archer is now carrying Surak's katra. (ENT 84: "Awakening")
• Unknown: Archer and T'Pol bring back the Kir'Shara, which contains Surak's original teachings; it will lead to vast changes on Vulcan. T'Pol's Pa'nar Syndrome is cured by T'Pau. (ENT 85: "Kir'Shara")
• Unknown: Dr. Emory Erickson, inventor of the transporter, conducts a long-range experiment in order to recover his lost son. (ENT 86: "Daedalus")
• Unknown: Organians test the Enterprise crew by observing their reactions to a deadly silicon-based infection. (ENT 87: "Observer Effect")

November

• November 12: Andorians threaten war on the Tellarites after apparently being attacked by a Tellarite vessel en route to trade talks. (ENT 88: "Babel One")
• November 14: Archer and Shran engage in mortal combat as Archer tries to unite the Andorians and Tellarites, who are being set at each other's throats by a remote-controlled Romulan vessel. (ENT 89: "United")
• November 16: The Romulan drone ship that attacked the Andorians is under the control of an Aenar, an offshoot race of the Andorians. Archer and Shran join forces to rescue the Aenar and stop the Romulan plot. (ENT 90: "The Aenar")
• November 24: "Have Beagle, Will Travel: The Legend of Porthos" (Framing Story) (Tales From the Captain's Table) (ENT)
• November 27: Phlox is kidnapped by the Klingons, who are seeking to cure a disease caused by an attempt to create Klingon/Augment hybrids; T'Pol's mental abilities grow after she conducts her first mind meld. (ENT 91: "Affliction")

December

• December 1: With Columbia's help, the Enterprise crew grapples with sabotage to their ship as they pursue the truth behind the kidnapping of Phlox. The disease is cured, but genetic mutations will make many Klingons appear Human-like for generations to come. (ENT 92: "Divergence")
• December 27: As a gift for negotiating with the Orion Syndicate, Archer receives three Orion slave girls, but these "gifts" have their own agenda. Meanwhile, Trip and T'Pol come to terms with the psychic bond that has been created between them. (ENT 93: "Bound")

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